Skin diseases: Hyperhidrosis and melanoma


Discover this pathology related to body sweating, as well as some of the symptoms and possible solutions to the problem.

The sweat is a normal process by which the body regulates temperature, but some people have excessive and heavy sweating, which can represent you a problem. The hyperhidrosis is excessive sweating in some part of the body such as hands or feet.

What problems does hyperhidrosis cause?

The hyperhidrosis cause discomfort and problems fundamentally relationship. People with excessive sweat on their hands, for example, may get papers wet when writing or may feel self-conscious when shaking hands with others. The effect of wet clothes, or the bad smell that sweat causes on the feet can also be unpleasant for the patient or his peers.

It has a solution?

There are treatments for hyperhidrosis:

  • Antiperspirants: Topical cream, spray, or roll-on antiperspirants are often the first treatment patients try. They are very similar to each other, as they all contain a variable concentration of aluminum hydroxide. They control hyperhidrosis to a certain extent, and have a rebound effect when they stop being applied.
  • Iontophoresis: consists of treating the area that sweats with a device that uses electrical current. It requires time, since the patient has to carry out the treatment very constantly, and in the warmer times of the year he must do it practically every day. These devices can be expensive, and treatment success cannot be guaranteed for all patients.
  • Botulinum toxin: the well-known toxin, known to the general public because it is used to treat expression lines, can be used to treat hyperhidrosis. If injected into areas that sweat excessively, it is able to paralyze the sweat glands and stop the area from sweating. It is an expensive treatment and is generally not covered by public medicine.
  • Sympathectomy: this is an operation that must be performed under general anesthesia . It consists of accessing the nerves that control sweating in the hands by thoracoscopy and blocking them so that they do not stimulate the sweat glands. Like any surgical intervention, it can have its risks and complications. The main one is that some patients have rebound sweating in some other part of the body when sweat is blocked in one area of ​​the skin. An obvious drawback of this operation is that it only serves to treat hand sweat.

Who can advise me on the best treatment for

In principle, the patient should go to a dermatologist who will explain the best options in their particular case. Some dermatologists perform botulinum toxin treatment. However, sympathectomy is performed by thoracic surgeons.


  • What it is: excessive sweating somewhere on the body.
  • Treatments: antiperspirants, botulinum toxin, iontophoresis and sympathectomy.
  • Consult: the best skin specialist delhi is the one who will advise the most appropriate treatment.

The ultimate against melanoma

Until now, treatment options for patients with advanced melanoma have been few and far between. However, at present, new drugs and chemotherapy and radiotherapy modalities are managing to increase the life expectancy of patients.

Until now, treatment options for patients with advanced melanoma have been few and far between. However, at present, new drugs and chemotherapy and radiotherapy modalities are managing to increase the life expectancy of patients. We detail the latest against melanoma.



  • Despite the fact that advanced melanoma is an incurable disease, new treatments are succeeding in significantly prolonging the survival of patients.
  • Tailored treatment: the new treatments take into account the genetic and molecular profile of cancer cells in each patient, so they are much more precisely directed against them.
  • Not all new drugs are routinely given anymore, although this will happen shortly.

What is your treatment based on now?

for malignant cells do not go too deep into the skin. In more advanced stages, it is very likely that the melanoma has already spread to the nodes or other organs. The chemotherapy or radiotherapy commonly used to date are not very effective in treatment and have not been able to significantly prolong the survival of patients.

What’s New in Melanoma Chemotherapy?

The discovery of new pathways by which cancer cells grow and spread throughout the body is leading to the development of new drugs that can stop these pathways. These new treatments are of interest to patients with metastatic melanoma, that is, melanoma that has spread to other organs. They are basically two types of drugs:

  • Ipilimumab : is part of the medicines known as monoclonal antibodies. It does not attack cancer cells but activates the immune system to fight them. What it does is activate cells that fight against the tumor, T lymphocytes.
  • Vemurafenib : It is another monoclonal that prevents tumor cells from growing by blocking a gene called BRAF. It is only useful for patients who have a mutation in this gene, so it is not a suitable treatment for all cases. Approximately half of melanomas have the mutation so they can be treated with vemurafenib.

These drugs, as well as newer ones, can generally be given to patients in clinical trials. Not all of them are administered routinely anymore, although this will happen shortly.

What can these new drugs achieve?

Until now, treatment options for patients with advanced melanoma have been few and far between. Currently, combinations of the new drugs mentioned with other chemotherapy and radiotherapy modalities are managing to increase the life expectancy of patients. Unfortunately, advanced melanoma remains an incurable disease. The goal of treatment should be to make it chronic for as long as possible, and ensure an acceptable quality of life for patients.

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